Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSEQVMVELRLIEQTFRLATTSDKREELERAAELLNEKFNDMRRSAPRVEHNKLVIMVALQLTQEVLSLNKSLQE-YAHCERLLQTILEDVEQIV 1T3U Chain:B ((4-95)) ---SNTLTVQILDKEYCINCPDDERANLESAARYLDGKMREIRSSGKVIGADRVAVMAALNITHDLLHRKERLDQESSSTRERVRELLDRVDRAL

General information: TITO was launched using: RESULT: Template: 1T3U.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 158 -20878 -132.14 -229.43 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain B : 0.83 3D Compatibility (PKB) : -132.14 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.546

(partial model without unconserved sides chains): PDB file : Tito_1T3U.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1T3U-query.scw PDB file : Tito_Scwrl_1T3U.pdb: