Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEHWLEFMGNHPILFGTLGVLIVLFFIFEGQRNGRKISPQSLGILVKAKNALLIDLRDSKDFREGHISGSRNI-----------------PYSQIASHADELKASDRP-LVFICNLGQVAGSA------LQKVAHHDSYRLDGGISNWKAQGLPLVKSKPKA 1E0C Chain:A ((11-130)) ------------------------------------IEPADLQARLSAPELILVDLTSAARYAEGHIPGARFVDPKRTQLGQPPAPGLQPPREQLESLFGEL--GHRPEAVYVVYDDEGGGWAGRFIWLLDVIGQQRYHYLNGGLTAWLAEDRPLSRELP--

General information: TITO was launched using: RESULT: Template: 1E0C.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 338 -18561 -54.91 -193.34 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -54.91 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.428

(partial model without unconserved sides chains): PDB file : Tito_1E0C.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1E0C-query.scw PDB file : Tito_Scwrl_1E0C.pdb: