Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MWKYLFSIFCLGANIHCYATDFGATNNFVSPNLQLKQNILPPTPKNIPLPAFGQRIIGWGTGAEGARQRLENIQPADVSMIKKQGTTLEMITAWQDFYEQEQQRNENNPTAKYRARLMKKIADLW- 1V74 Chain:B ((1-87)) MNKM--------------------------AMIDLAKLFLAS---KITAIEFSERICV-------ERRRLYGVKDLS-PNILNCGEELFMAAE--RFEPDADRANYEIDDNGLKVEVRSILEKFKL

General information: TITO was launched using: RESULT: Template: 1V74.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 288 -30105 -104.53 -350.05 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain B : 0.61 3D Compatibility (PKB) : -104.53 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.293

(partial model without unconserved sides chains): PDB file : Tito_1V74.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1V74-query.scw PDB file : Tito_Scwrl_1V74.pdb: