Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSLTDILVCLSEKQNGRRNNMSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALVGNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATL-IRKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALFSFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQI-GMIGMIVSLVVVLTVANISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALLFTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDWIPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLF-PLFAITTI--APQHLDITQSWVAW----GLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA 2Z07 Chain:A ((3-420)) -----------PLRTKAVEVLQRNSRGAFTVP-----------AHGLYPYQWLWDSAFIALGWT------------------------QVDWERAWQELLCLFDYGQ----------GPDGMLPHIVFHEQSRDY---------------FAQPATSGITQPPVVATVVRYLYEKDPD--RDRARERARYLFPKLLAFHRWLYHARDPYRTGLVVIVHPWESGMDNSPAWDKPLSRVPVKHVNPDYDRYLSLLYLFRRLEYDPREIYRQSPF----KVVDVGFNAILQRANRDLYALAVLLQEDPYEIEEWIVRGEVGLEALWDREAGFYFSWDLVAGEPIAVKTSAGFLPLFAG-TPHQGRASLLAQEAERWGEKARYLLPSVDPTSPFFEPGRYWRGPVWINVNWMVAEGFRDYGFAALAARLKADALALMEREGFREYYDPLTGQGRGGEGFSWSAALALFWTR-------

General information: TITO was launched using: RESULT: Template: 2Z07.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2199 -198952 -90.47 -523.56 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.56 3D Compatibility (PKB) : -90.47 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.56 QMean score : 0.234

(partial model without unconserved sides chains): PDB file : Tito_2Z07.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2Z07-query.scw PDB file : Tito_Scwrl_2Z07.pdb: