Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence WYKPEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLAMKVSSPPPTIMQQNKKGDMTHELVRHFLIETGPR------------------GVKLKGCPNEPNFGSLSALVYQH 2EYZ Chain:A ((13-104)) WYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSVSEN-----------------SRVSHYIINSSGPRPPVPPSPAQPPPGVSPSRLRI-G---DQEFDSLPALLEFY

General information: TITO was launched using: RESULT: Template: 2EYZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 272 -12642 -46.48 -170.83 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -46.48 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.443

(partial model without unconserved sides chains): PDB file : Tito_2EYZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2EYZ-query.scw PDB file : Tito_Scwrl_2EYZ.pdb: