Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence LGCTYSLYNNIGRQLVSYAPVSPGGTIDYKIGRT-THKLKFADTCEFEKS----VPRLPDYWKVFGHVEGQMMPVE 4IAJ Chain:B ((8-47)) -------------------------EITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQ-----------

General information: TITO was launched using: RESULT: Template: 4IAJ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 57 -1528 -26.81 -43.66 target 2D structure prediction score : 0.74 Monomeric hydrophicity matching model chain B : 0.59 3D Compatibility (PKB) : -26.81 2D Compatibility (Sec. Struct. Predict.) : 0.74 1D Compatibility (Hydrophobicity) : 0.59 QMean score : 0.336

(partial model without unconserved sides chains): PDB file : Tito_4IAJ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4IAJ-query.scw PDB file : Tito_Scwrl_4IAJ.pdb: