Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKLLKRQILRRRRHFMIFNQD-----EIYVIAEIGVNHNGSVDLAKELILKAKDCGANAVKFQTFKADSLLSDQTEMAAYQKENTGSSQSQLELVKSLELTYEQTEEIKKFCDEQKITFISTPFDSDSLKFLVNEIDVPYLKVSSADISNLPFLYEIACSKKHVILSTGTASLGDIEQALSVFAFVIDKGTEVQPSQQLFREAYSKISVRKQLKQQVSILHCVTQYPALFEESNLKAISTLKNVF-DLATGFSDHTLDEYAAVISVSLGARIFEKHITLDKTMAGPDHAASMEPNEFKHYVEILHKTHAALGDGIKFMLEQESDNYYLVRRSIVAKTDIAEGELLTADNITTKRAGRVCLEPNKYWDVIGTKAKRSFKKNDFIEI 1XUZ Chain:A ((2-340)) ---------QNNNEFKIGNRSVGYNHEPLIICEIGINHEGSLKTAFEMVDAAYNAGAEVVKHQTHIVEDEMSDE----AKQVIPGNADVSIYEIMERCALNEEDEIKLKEYVESKGMIFISTPF-SRAAALRLQRMDIPAYKIGSGECNNYPLIKLVASFGKPIILSTGMNSIESIKKSV-----------------EIIREA----------GVPYALLHCTNIYPTPYEDVRLGGMNDLSEAFPDAIIGLSDHTLDNYACLGAVALGGSILERHFTDRMDRPGPDIVCSMNPDTFKELKQGAHALKLARGGKKDTIIAGEKPTKDFAFASVVADKDIKKGELLSGDNLWVKRPGNGDFSVNEYETLFGKVAACNIRKG-----

General information: TITO was launched using: RESULT: Template: 1XUZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1719 75863 44.13 227.82 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.74 3D Compatibility (PKB) : 44.13 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.447

(partial model without unconserved sides chains): PDB file : Tito_1XUZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1XUZ-query.scw PDB file : Tito_Scwrl_1XUZ.pdb: