Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRSLLGDHLLQRLQQDTEGKLHQRLFRCLRGAIIDGVIQPKTRLPASRDLASEIHVSRNTVLTAYEQLQAEGYLEALTGHGTWVAEKLPESFLNTQNKKKVVSSPNVQSSYALSQRGSNLLGYAAASPHQWGAFVPGAPDVTEFPHHIFSRIQARLSREPDINRLIYSNAGGCIELRSALADYLRVARSVQCDADQIIITEGIHQAIDLVSRALSDMGDKVW-IEDPAYWGMRNTLRINGLDIQPMPVDAEGIIPEENPAVPPKLIFVTPSHQYPLGSHLSLDRRRQLIQIARQH-NSWIVEDDYDSEFRFSGQPYPSLQGLENNAPVLYMGTFSKTIYPSLRIGYLVVPKPLFSPLRIVAAELYRGGHLLEQKALAEFIREGHYEAHIRRMRLLYGKRRDYLVSLIQRYLGPEFIHEYDEAAGLHLVLKLPNSCDDVAIAATALERGVKVRPLSQYYMQSHAH-AERGLLMGFACVNEKDMVMAFGVLLQYLREADVPTLN 4N0B Chain:A ((16-457)) --------------------IYQQIYQKLKKEILSRNLLPHSKVPSKRELAENLKVSVNSVNSAYQQLLAEGYLYAIERKGFFVEE------LD-------MFSAEEHPPFALP----DDLKEIHIDQSDWISFSHMSSDTDHFPIKSWFRCEQKAASRSYRTLGDMSHPQGIYEVRAAITRLISLTRGVKCRPEQMIIGAGTQVLMQLLTELLPK--EAVYAMEEPGYRRMYQLLKNAGKQVKTIMLDEKGMSIAEITRQQPDVLVTTPSHQFPSGTIMPVSRRIQLLNWAAEEPRRYIIEDDYDSEFTYDVDSIPALQSLDRFQNVIYMGTFSKSLLPGLRISYMVLPPELLRAYKQRGYDLQTCSSLT-QLTLQEFIESGEYQKHIKKMKQHYKEKRERLITALEAEFSGE-VTVKGANAGLHFVTEFDTRRTEQDILSHAAGLQLEIFGMSRFNLKE---TGRPALIIGFARLKEEDI--------------------

General information: TITO was launched using: RESULT: Template: 4N0B.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2069 -84265 -40.73 -193.71 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.77 3D Compatibility (PKB) : -40.73 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.468

(partial model without unconserved sides chains): PDB file : Tito_4N0B.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4N0B-query.scw PDB file : Tito_Scwrl_4N0B.pdb: