Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MHLNSSIDKKMTTLNILFKTTSLCLAMALLVGCNDNDDNDSSTPAPRSNQTVNILAFNDFHGNLEPPKRYVEAANPNDASQTVRIPVGGVSYFADAIKKLKAQNPNNVVVSAGDLISASPLTSSLFLDEPTIEVMNDIQIDFNAVGNHEFDRGTDELRRLQNGGCQQYTSTAPCQINKNFSGAKFNFLAANVAMKNDTSKTIFPAYKVKTYGGIPVAFIGLT-LKATPSIVSAAGIKDVEFRDEADTVNALIPELQKQGIEAIVVVVHEGAAPSTKLNQKTCDGLSGPILGILDR------LNPAVDIVVSGHTHQSYICDYATKNPAKPFLLTSAGQYGTLITDIKVGLDGKTGDIIKKDAKQIPVQSEAYTSGTTTVSLTDLY-QKFSKTPSIEAILDKYRQAVTTISGRVVGTSTAVVSRTQVESGESPLGDMIADAQQAAALQASNQGSDFTLMNPGGVRADLLINSSNQITFGDIFAVQPFGNSIVTLSLTGKQIRDVLEQQWSGANANSPRILQPSKELSYQYAANTSVSPRASNIMVAGSPLVDTKVYRVTVNSFLADGGDNFTVLKEGQNRVGGGQDIDALESYVAQNSKDSPLIIPATTRIKVIK 3IVD Chain:A ((7-465)) ---------------------------------------------------VTIIYTNDLHAHVEPYKVPWIADGKRD--------IGGWANITTLVKQEKAKNKATWFFDAGDYFTG-PYISSLTKGKAIIDIMNTMPFDAVTIGNHEFDHGWDNTL-LQ------------------LSQAKFPIVQGNIFYQNSSKSFWDKPYTIIEKDGVKIGVIGLHGVFAFNDTVSAATRVGIEARDEIKWLQRYIDELKGK-VDLTVALIHEGV-PARQSSMGGTD-----VRRALDKDIQTASQVKGLDILITGHAH------VGTPEPIK------VGNTLILSTD-SGGID--VGKLVL-DYKEKP-----HNFTVKNFELKTIYADEWKPDQQTKQVIDGWNKKLDEVVQQTVAQSPVELKRAYGESAS------LGNLAADALLAAAGKNTQLALTNSGGIRNEI---PAGAITMGGVISTFPFPNELVTMELTGKQLRSLMEHGASLSNG----VLQVSKGLEMKYDSSKPVGQRVITLTLNGKPIEDATVYHIATQSFLADGGDGFTAFTEGKAR-----------------------------------

General information: TITO was launched using: RESULT: Template: 3IVD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2790 -24124 -8.65 -53.49 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -8.65 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.371

(partial model without unconserved sides chains): PDB file : Tito_3IVD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3IVD-query.scw PDB file : Tito_Scwrl_3IVD.pdb: