Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSKGFKALTYIADDNIADTVTWLLHHQDVFETFHFDVLSQELSVTHAAGRDIIRVGTFLNATYGILVTSV 2NVA Chain:A ((249-268)) --------------------------------------------------IVAEPGRFFAEHYSVLATQV

General information: TITO was launched using: RESULT: Template: 2NVA.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 3 -513 -170.83 -25.63 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.56 3D Compatibility (PKB) : -170.83 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.56 QMean score : -0.109

(partial model without unconserved sides chains): PDB file : Tito_2NVA.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2NVA-query.scw PDB file : Tito_Scwrl_2NVA.pdb: