Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIGCLIGEVFALEAPTVLLNVNGVGYEIDTPLSTFCQL-QKGQKVTLWTHLVIREDAQQLYGFSDAQEKTIFRTLLKVNGVGPKMALGILSTLSVELLVHTIEHDDVNTLVKVPGVGKKTAERLMIELRDRFKTLAQGTSSAAALPQIQFVSNSPVA-------EAEAALQSLGYKPLEAQKAVAAVKADYTESADIIRAALKSMMK 1C7Y Chain:A ((1-203)) MIGRLRGIIIEKQPPLVLIEVGGVGYEVHMPMTCFYELPEAGQEAIVFTHFVVREDAQLLYGFNNKQERTLFKELIKTNGVGPKLALAILSGMSAQQFVNAVEREEVGALVKLPGIGKKTAERLIVEMKDRFKGLHGDLFTPAA----DLVLTS---ATDDAEQEAVAALVALGYKPQEASRMVSKIARPDASSETLIREALRAAL-

General information: TITO was launched using: RESULT: Template: 1C7Y.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 898 -47105 -52.45 -246.62 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.85 3D Compatibility (PKB) : -52.45 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.85 QMean score : 0.582

(partial model without unconserved sides chains): PDB file : Tito_1C7Y.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1C7Y-query.scw PDB file : Tito_Scwrl_1C7Y.pdb: