Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSDFLSEHLIYRDDDFMVIHKPSDILSVPGKGDLHDSVLTRL------VAIEPRTLLIHRLDRDTSGILVFGLSKRGQSAIARQFQDRQTSKIYEALVAGHLEGEGTVDIPVVYDPSRPPLHIVDASHNKPALTHWQAIEHFQIQGQPVTRVKLTPITGRSHQLRVHMQYLGHPIVGDTLY--------ATPEQLL-----VPRLCLHAKQLSFNHPVTGESLTFNCPVPF 1V9F Chain:A ((85-301)) --------IVYEDEDIIIINKPRDLVVHPGAGNPDGTVLNALLHYYPPIADVPRAGIVHRLDKDTTGLMVVAKTVPAQTRLVESLQRREITREYEAVAIGHMTAGGTVDEPISRHPTK-RTHMAVHPMGKPAVTHYRIMEHFRVH----TRLRLRLETGRTHQIRVHMAHITHPLVGDPVYGGRPRPPKGASEAFISTLRKFDRQALHATMLRLYHPISGIEMEWHAPIP-

General information: TITO was launched using: RESULT: Template: 1V9F.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 978 -18253 -18.66 -92.19 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain A : 0.79 3D Compatibility (PKB) : -18.66 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.425

(partial model without unconserved sides chains): PDB file : Tito_1V9F.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1V9F-query.scw PDB file : Tito_Scwrl_1V9F.pdb: