Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLLMIDNYDSFTYNIVQYFGELNQEVKVVRND---QVTLEDIERWQPKYLVIGPGPCSPSEVGISIPAINHFAGKIPLFGVCLGHQSIGQAFGGKIVRAKTVMHGRLSDMYHSNKGIFSNLPSPFSATRYHSLVIDQETLPDCLEVTCWTNEADGSMEEIMGVKHKTLPVEGVQFHPESILSQHGHQIFKNFLDIYA 1I7Q Chain:B ((4-187)) -ILLLDNVDSFTYNLVDQLRASGHQVVIYRNQIGAEVIIERLQHMEQPVLMLSPGPGTPSEAGCMPELLQRLRGQLPIIGICLGHQAIVEAYGGQVGQAGEILHGKASAIAHDGEGMFAGMANPLPVARYHSLV--GSNIPADLTVNARFGEM------VMAVRDDRRRVCGFQFHPESILTTHGARLLEQTL----

General information: TITO was launched using: RESULT: Template: 1I7Q.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1034 -42883 -41.47 -236.92 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain B : 0.83 3D Compatibility (PKB) : -41.47 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.354

(partial model without unconserved sides chains): PDB file : Tito_1I7Q.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1I7Q-query.scw PDB file : Tito_Scwrl_1I7Q.pdb: