Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAAFLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPATYLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCATDGKLALQAHGDDRNLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVL-DKAEDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSLINDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGL-ENVKEVALGCGG----VLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK 3ODP Chain:A ((5-392)) LLGYSEDYLKERKGYITAKEICNQPKLWRETYEIILSQREKLKSFLDNFAKKPN-AKIVITGAGSSAFVGNSVVSYLNA---KENIKIEAIATTDIVSHPFYYLKKDEPTLLISCARSGNSPESTAAVTLAEKIVDDISHLIITCNSEGKLALHAKRNYNSFLLLMPEESNDKGFAMTGSFSTMLLSCLLIFNLDKLESIGKQIESISMQGEKVLVNNVELMKKIVGEKFKRTVYLGAANAFGLAKESALKVLELTAGKIATLYDTPLGFRHGPKSIIDDETLIVIFFSNDTYAREYEYDLLKEVYSQNGNHKVLAISEYEDKLIEDNSDYFIAINKEEQEYEDDSFLSLDYLLNAQMYAFINSMELGIGPDNPCPTGEVNRVVKGVIIHDY--

General information: TITO was launched using: RESULT: Template: 3ODP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2328 -199425 -85.66 -522.05 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.87 3D Compatibility (PKB) : -85.66 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.87 QMean score : 0.549

(partial model without unconserved sides chains): PDB file : Tito_3ODP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3ODP-query.scw PDB file : Tito_Scwrl_3ODP.pdb: