Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEELIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTIRGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF 4UOG Chain:A ((4-133)) -ERTFIAVKPDGVQRGLIGEIIKRFEAKGFKLAGMKY-IQASEDLLKQHYIDLADKPFYPGLCKYMSSGPVVAMCWEGTGVVKTARVMMGETRPADSKPGTIRGDFCIEVG-----RNIIHGSDSVESANKEIALWF

General information: TITO was launched using: RESULT: Template: 4UOG.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 602 -73910 -122.77 -568.53 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.87 3D Compatibility (PKB) : -122.77 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.87 QMean score : 0.596

(partial model without unconserved sides chains): PDB file : Tito_4UOG.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4UOG-query.scw PDB file : Tito_Scwrl_4UOG.pdb: