Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTQVDIAALSPQVVWQHFQTLCTIPRPSKHEQQLREFLQNWAESRNLETYVDEVGNLIIRKNATPGKKHVSGVILQGHLDMVTQANTGTVHDFFKDPIRPVLEEGWLIAKDTTLGADNGIGVALALAVLDSNDI-HGPIEVLLTVDEEAGMSGARLLETGVLKGKWLFNIDTEEWGELYLGCAGSIDVEVEQPLNYEPIPENLNIVNIQVAGLKGGHSGVDIHLGRGNANVILARF---LNQHLASLGGHLVEFTGGTARNALPREAVATIAISPNQLSSLEKLLAEYQAAWKEQLKGIDDNLQLSIQSTGAKVTEVINQQQQNEWLQALATSPYGVASMSQVLPDVVETSNNIGVVRLNREGGKAILMVRSMVNQEAQDFAEKIQ--AHFSQFNIGSTLTPLVSGWTPNPDSAALKCLQQAYQNAFNIEPNLKVIHAGLECGIIAEHYPHLQMVSFGPDIQGAHAPGERVKVDTVEKCWKLLVTALASVE 2QYV Chain:A ((6-484)) ------QSLQPKLLWQWFDQICAIPHPSYKEEQLAQFIINWAKTKGFFAERDEVGNVLIRKPATVGMENRKPVVLQAHLDMVPQ----------QDPILPYIDGDWVKAKGTTLGADNGIGMASALAVLESNDIAHPELEVLLTMTEERGMEGAIGLRPNWLRSEILINTDTEENGEIYIGCAGGENADLELPIEYQ-VNNFEHCYQVVLKGLRGGHSGVDIHTGRANAIKVLLRFLAELQQNQPHFDFTLANIRGGSIRNAIPRESVATLVFN-GDITVLQSAVQKFADVIKAELALTEPNLIFTLEKV-EKPQQVFSSQCTKNIIHCLNVLPNGVVRNSDVIENVVETSLSIGVLKTEDNFVRSTMLVRSLIESGKSYVASLLKSLASLAQGNI--NLSGDYPGWEPQSHSDILDLTKTIYAQVLGTDPEIKVIHAGLECGLLKKIYPTIDMVSIGPTIRNAHSPDEKVHIPAVETYWKVLTGILAHI-

General information: TITO was launched using: RESULT: Template: 2QYV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2743 -26060 -9.50 -56.28 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.81 3D Compatibility (PKB) : -9.50 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.81 QMean score : 0.506

(partial model without unconserved sides chains): PDB file : Tito_2QYV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2QYV-query.scw PDB file : Tito_Scwrl_2QYV.pdb: