Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKPDISELSVEELKRLQEEAEALIASKKDQAIEDAYNQIIEIAENVGFSVEQLLEFGAQKRKKTTRKSVEPRYRNKNNAEETWTGRGKQPRWLVAEIEKGAKLEDFLI 2LRX Chain:A ((9-45)) -----------------------------------------------------------------------KFTDVNGETKTWTGQGRTPKPIAQALAEGKSLDDFLI

General information: TITO was launched using: RESULT: Template: 2LRX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 104 -815 -7.83 -22.01 target 2D structure prediction score : 0.95 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : -7.83 2D Compatibility (Sec. Struct. Predict.) : 0.95 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.807

(partial model without unconserved sides chains): PDB file : Tito_2LRX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2LRX-query.scw PDB file : Tito_Scwrl_2LRX.pdb: