Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGK----PFDENPEAQELLSLGIKVITGSHPIELLDEEF---SLMVKNPGIPYSHPLVAKAQEMGIPVITEVELAYEVAECPIIGITGTNGKTTTTTMTGLLLNA-GADQGIARLAGNIGYPASGVAQEAKSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTEKDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYY---------KKEKIMEISELGVPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKATNILATKMALSGFETSKVV-LLAGGLDRGNTFDELIPSLKGIKA-MVVFGQTKEKLMDAGKKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVNRLK 1E0D Chain:A ((1-429)) ----ADYQGKNVVIIGLGLTGLSCVDFFLARGVTPRVMDTRMTPPGLDKLPEAVE-----------RHTGSLNDEWLMAADLIVASPGIALAHPSLSAAADAGIEIVGDIELFCREAQAPIVAITGSNGKSTVTTLVGEMAKAAGVNVGVG---GNIGLPALMLLDD--ECELYVLELSSFQLETTSSLQAVAATILNVTED-----FGLQQYRAAKLRIYEN---AKVCVVNADDA-LTMPI--ADERCVSF--------GVNMGDYHLNHQQGETWLRVKGEKVLNVKEMKLSGQHNYTNALAALALADAAGLPRASSLKALTTFTGLPHRFEVVLEHNGVRWINDSKATNVGSTEAALNGLHVDGTLHLLLGGDGKSADFSPLARYLNGDNVRLYCFGRDGAQLAALRPEVAEQT----ETMEQAMRLLAPRVQPGDMVLLSPACASLDQFKNFEQRGNEF--------

General information: TITO was launched using: RESULT: Template: 1E0D.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2356 -5225 -2.22 -13.00 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -2.22 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.510

(partial model without unconserved sides chains): PDB file : Tito_1E0D.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1E0D-query.scw PDB file : Tito_Scwrl_1E0D.pdb: