Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFLYNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKV----QGLDISSTAVSQARENDIPAYQEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRAEEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAI----ERGYLYAGASGSGHFLKMIHNGIEYGMMQAIGEGFQLVQK--SEYAFDLEQVARVWNHGSVIRGWLMEIMED---QLNEHPNLSNYRGIVSASGE---AKWTVETALEMAVPVPVIATSLFMRNLSQEEDSFSAKVVSALRNGFGGHEIVEKGE 2W8Z Chain:A ((6-295)) --------------------------------------------------------QIGVIGLAVMGKNLALNIESKGYSVAVYNRLREKTDEFLQEAKGKNIVGTYSIEEFVNALEKPRKILLMVKAGAPTDATIEQLKPHLEKGDIVIDGGNTYFKDTQRRNKELAELGIHFIGTGVSGGEEGALKGPSIMPGGQKEAHELVRPIFEAIAAKVDGEPCTTYIGPDGAGHYVKMVHNGIEYGDMQLIAEAYFLLKHVLGMDAAELHEVFADWNKGE-LNSYLIEITADIFTKIDEETGKPLVDVILDKAGQKGTGKWTSQNALDLGVPLPIITESVFARFLSAMKD------------------------

General information: TITO was launched using: RESULT: Template: 2W8Z.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1296 35851 27.66 130.84 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : 27.66 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.391

(partial model without unconserved sides chains): PDB file : Tito_2W8Z.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2W8Z-query.scw PDB file : Tito_Scwrl_2W8Z.pdb: