Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence PVNLQEVRSNDQQLHPYRCKFE--VLHIWYTEPFLSSFIDPGQRAEITI-EARARKTDFAIDIDGECKGTKVKG----AGRIPENW----FIRLSREGSKEVQF-INDK-----------PKNNRVSGGS- 1Q5H Chain:A ((7-133)) -MQLRFARLSEHATAPTRGSARAAGYDLYSAYDYT---IPPMEKAVVKTDIQIALPSGCYGRVAPRSGLAAKHFIDVGAGVIDEDYRGNVGVVLFNFGKEKFEVKKGDRIAQLICERIFYPEIEEVQALDD

General information: TITO was launched using: RESULT: Template: 1Q5H.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 398 26007 65.34 252.50 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : 65.34 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.349

(partial model without unconserved sides chains): PDB file : Tito_1Q5H.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1Q5H-query.scw PDB file : Tito_Scwrl_1Q5H.pdb: