Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQLYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPALLDQSGTEDVRVFESAHILLYLAEKFG---AFLPSNPVEKVEVLNWLFWQA-GAAPFLGGGFGHFFNYAPEKLEYPI--NRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLVQGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK 4F0C Chain:A ((16-219)) --------------------------------------------------PNGWKVDMLLREL------GLSFETVYVNLGQREHKSPSFTKYNPNGRIPALIDHY-YNDFVVWESDAILLYIVEKYDPEHKFSVSTFDDKIIMTQWLFFQASGQGPYFGQA-GWFLAVAPPEERNPTIAERYQKEILRVFGVLESVLSQRQWLVADKLTIADISFVIWNATAV-NLLVKGYKGFDFEKDFPSVHRWHTALITRPAIAESLKT------

General information: TITO was launched using: RESULT: Template: 4F0C.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 850 -41605 -48.95 -210.12 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -48.95 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.495

(partial model without unconserved sides chains): PDB file : Tito_4F0C.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4F0C-query.scw PDB file : Tito_Scwrl_4F0C.pdb: