Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRSLLGDHLLQRLQQDTEGKLHQRLFRCLRGAIIDGVIQPKTRLPASRDLASEIHVSRNTVLTAYEQLQAEGYLEALTGHGTWVAEKLPESFLNTQNKKKVVSSPNVQSSYALSQRGSNLLGYAAASPHQWGAFVPGAPDVTEFPHHIFSRIQARLSREPDINRLIYSNAGGCIELRSALADYLRVARSVQCDADQIIITEGIHQAIDLVSRALSDMGDKVWIEDPAYWGMRNTLRINGLDIQPMPVDAEGIIPE--------------ENPAV-PPKLIFVTPSHQYPLGSHLSLDRRRQLIQIARQHNSWIVEDDYDSEFRFSGQPYPSLQGLENNAPVLYMGTFSKTIYPSLRIGYLVVPKPLFSP--LRIVAAELYRG--GHLLEQKALAEFIREGHYEAHIRRMRLLYGKRRDYLVSLIQRYLGPEFIHEYDEAAGLHLVLKLPNSCDDVA--IAATALERGVKVRPLSQYYMQSHAHAERGLLMGFACVNEKDMVMAFGVLLQYLREADVPTLN 4GE7 Chain:A ((111-424)) ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LCVTSGSQQGLCKVFEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIVPDSLRDILSRWKPEDAKNPQKNTPKFLYTVPNGNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNSGRVPTFLSMDVDGRVIRADSFSKIISSGLRIGFLTGPKPLIERVILHIQVSTLHPSTFNQLMISQLLHEWGEEG-FMAHVDRVIDFYSNQKDAILAAADKWLT-GLAEWHVPAAGMFLWIKV-KGINDVKELIEEKAVKMGVLMLPGNAFYVDSSAPSPY-LRASFSSASPEQMDVAFQVLAQLIKES------

General information: TITO was launched using: RESULT: Template: 4GE7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1470 -54590 -37.14 -186.31 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : -37.14 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.519

(partial model without unconserved sides chains): PDB file : Tito_4GE7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4GE7-query.scw PDB file : Tito_Scwrl_4GE7.pdb: