Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKIVADENLAFTDYFFSEFGDIQHKAGRTLTHTDVQDAEALLVRSVTAVNESLIQNTALKYVGSATIGTDHLDIQALEKQGITWANAAGCNAQAVAEYVITALLHL------------DASLLEQQEKF-------------TLGIVGLGNVGKRLAYMAQLLGWKVIGFDPFVQLDSIEN-------VSFQTLLQQANAVSIHVPLTKKGEHATYHLFDEKAFAALQPNTILINSARGPVVKEAALIEDIQCTQ-RKVVLDVFEHEPV-ISEGLLNMLA--LATPHIAGYSLEGKARGTQMIYEAFCQKFGYDINKRFETQLPACEDYFSGHDLKAVLKQKLSQIYDIAQYDANIRACVKEGKVEQKAFDLLRKNYPLRREWAAHGGPQA 2OME Chain:A ((51-298)) ---------------------------------------AMMYHTITLTREDLEKFKALRVIVRIGSGYDNVDIKAAGELGIAVCNIPSAAVEETADSTICHILNLYRRNTWLYQALREGTRVQSVEQIREVASGAARIRGETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPYLQ-DGIERSLGVQRVYTLQDLLYQSDCVSLHCNLN---EH-NHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYS---------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 2OME.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 903 -52556 -58.20 -247.90 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -58.20 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.464

(partial model without unconserved sides chains): PDB file : Tito_2OME.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2OME-query.scw PDB file : Tito_Scwrl_2OME.pdb: