Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLHLHVHPENPQQRLIEQAVERIRAGDVVVYPTDAAYAIGCQIGNKNAMERIAQIRGLGPKHQYAIMCCDLSDIATYAKVDNATYRLLKANTPAITTFILPATS-EVPRRLMHPKKKTIGLRIPSNPICQALLKELGGPLLTSTLILPGQEDPLDDPYDIENQLAKRIDVFIDGGFGTL--TTTSIVDLSGEHPEIIRHGVGDVSAFE 3TTD Chain:A ((109-290)) ----------EQEAALQAAIAQLKMGNIVAIKGIGGFHLACDARNSNAVATLRARKHRP-AKPLAVMLPVADGLPD------AARQLLTT-PAAPIVLVDKKYVPELCDDI-APGLNEVGVMLPANPLQHLLLQELQCPLVMTSGNLSGKPPA-ISNEQALEDLQGIADGFLIHNRDIVQRMDDSVVRESG---EMLRRSRGYVP---

General information: TITO was launched using: RESULT: Template: 3TTD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 931 -84468 -90.73 -471.89 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -90.73 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.606

(partial model without unconserved sides chains): PDB file : Tito_3TTD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3TTD-query.scw PDB file : Tito_Scwrl_3TTD.pdb: