Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKMFTKLALVSSLAISANAMAMQSMDDAALSAATGQDGINIGIALGTSGISIDKLYLHDNDGLATTTGITGATGTAGALAISDVTLKQTGTGNLLDLAIDTNGASST---NGAFLNVAATVGAVDIHVGSIGVGTSGTVNETTALRGITETAPTEIISGLDLS--LGQITANVQLGSTPQGAMIK--VDSALKGGLTISNLGINDAAGGGSILLDKVMVRGAGNATGDLDVKADISVTGNGLQVKSTSAQDMNVYVGGVHLGTNTKASDGTWGTGAVKAASIGDLEIQGLNVANTTITISGH 4CG0 Chain:A ((20-212)) ----------------------------------------------------------------------GLTGSGVKVAVLDTGISTHPDLNIRGGASFVPGEPSTQDGNGHGTHVAGTIAALNNSIGVLGVAPSAELYAVKVLGASGSGSVSSIAQGLEWAGNNGMHVANLSLGSPSPSATLEQAVNSATSRGVLVVAASGNSGAGSISYPARYANAMAVG-ATDQNNNRASFSQYGAGLDIVAPGVNVQSTYPGSTYASLN--------------------------------------

General information: TITO was launched using: RESULT: Template: 4CG0.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1112 -13935 -12.53 -74.92 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -12.53 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.260

(partial model without unconserved sides chains): PDB file : Tito_4CG0.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4CG0-query.scw PDB file : Tito_Scwrl_4CG0.pdb: