Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -----------------------MKKSSILFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGVS---------IFLALFYMIPA----------LYFLFRIGKKWELPKKVLILSLLGGMF--LSGWLSSFANTYIHDLLGVLFPDSPFLNAF-ESAIVAPLVEEPLKLLPLVFVLALIPVRKLKFLFLLGIASGLGFQMIEDIG------------YIRTDLPEGFDFTISRILERII----SGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLIV 5WWM Chain:A ((10-323)) DWTASILDQAQAPESVADFERLLIGNPNSSVVWMNYMAFQLQLSE---IEKARELAERALKTINFREEAEKLNIWIAMLNLENTFGTEETLEEVFSRACQYMDSYTIHTKLLGIYEISEKFDKAAELFKATAKKFGGEKVSIWVSWGDFLISHNEEQEARTILGNALKALPKRNHIEV--VRKFAQLEFAKGDPERGRSLFEGLVADAPKRIDLWNVYVDQEVKAKDKKKVEDLFERIITKKITRKQAKFFFNKWLQFEESKTIEYVKAKATEYVAS---

General information: TITO was launched using: RESULT: Template: 5WWM.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 838 -19595 -23.38 -92.87 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -23.38 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.287

(partial model without unconserved sides chains): PDB file : Tito_5WWM.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5WWM-query.scw PDB file : Tito_Scwrl_5WWM.pdb: