Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVATNGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAVNNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQLEAYNAEHT-DNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVIELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK 3H7M Chain:A ((23-230)) -----------------------------------------------PYEFI-DQNGKPAGYNVELTRAI-AEVMGMTVEFRLGAWSEMFSALKSGRVDV-LQGISWSEKRARQIDFTPPHTIVYHAIFARRDSPPAAGLEDLRGRKV----ALHRDGIMHEYLAERGYGKDLVLTPTPADALRL---LAAGGCDYAVVAMVPGMYIIRENRLTNLVPVARSIAAQRYGY-AVRQGDAELLARFSEGLAILRKTGQYEAIRAKWLG-----------

General information: TITO was launched using: RESULT: Template: 3H7M.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1010 -53903 -53.37 -260.40 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -53.37 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.368

(partial model without unconserved sides chains): PDB file : Tito_3H7M.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3H7M-query.scw PDB file : Tito_Scwrl_3H7M.pdb: