Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEVVMDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGRKVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD 2K5E Chain:A ((1-67)) ----MTQKFTKDMTFAQALQTHPGVAGVLRSYNLGCIGCMG-----AQNESLEQGANAHGLNVEDILRDLNALALE-----

General information: TITO was launched using: RESULT: Template: 2K5E.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 251 -37711 -150.24 -562.84 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -150.24 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.586

(partial model without unconserved sides chains): PDB file : Tito_2K5E.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2K5E-query.scw PDB file : Tito_Scwrl_2K5E.pdb: