Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKNILKKKGVTGLFKMKSCN----LDQALHE-HFSEEELAGHFHVLLWTFLQWHCYHTQYLSKRLVRKLYCS-SSSKFPNC-------------------------------------------------------------------------------------------------------------------------------------------------- 2AXO Chain:A ((38-266)) AQEAV---KGVVELFTSQGCASCPPADEALRKMIQKGDVVGLSYHVDYWNYLGWTD---SLASKENTERQYGYMRALGRNGVYTPQAILNGRDHVKGADVRGIYDRLDAFKREGQGLNVPVSSKFAGDEVEIDIGAGNGKADVVVAYFTREQTVDVKKMSYWHSVYDVQTVGMWDGSPMTVKLPASVVAKVKKGGCAVLLQTANASGDPAAIVGASILLGNETQLEHH

General information: TITO was launched using: RESULT: Template: 2AXO.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 209 -13217 -63.24 -188.81 target 2D structure prediction score : 0.47 Monomeric hydrophicity matching model chain A : 0.56 3D Compatibility (PKB) : -63.24 2D Compatibility (Sec. Struct. Predict.) : 0.47 1D Compatibility (Hydrophobicity) : 0.56 QMean score : 0.428

(partial model without unconserved sides chains): PDB file : Tito_2AXO.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2AXO-query.scw PDB file : Tito_Scwrl_2AXO.pdb: