Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKIDILTLFPEMFSPL-EHSIVGKAREKGLLDIQYHNFRE-NAEKARHVDDEPYGGGQGMLLRVQPIFDSFDAIEKKNPR---VILLDPAGKQFDQAYAEDLAQEEELIFICGHYEGYDER-IKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSHQDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLLEHYQLTVEEEKMLAEIKENKE 4YQG Chain:A ((9-249)) MWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLG-----------DGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQ----

General information: TITO was launched using: RESULT: Template: 4YQG.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 941 37462 39.81 167.24 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.86 3D Compatibility (PKB) : 39.81 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.86 QMean score : 0.496

(partial model without unconserved sides chains): PDB file : Tito_4YQG.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4YQG-query.scw PDB file : Tito_Scwrl_4YQG.pdb: