Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence --MKMLAQLQNRF--DQWVEQIVQYLDRL-----SVRERIMVVFT-TIFVVVVIVG-YSLWKMHSLAEQQQKRLNDLK--DLMVWMQSNAVTMKPANELELDKSGKIQRVAQQQGLTV---SSQQNGEQL---QIVVTHQNYAILANFLIQLAQMGLS--IQKMEMVSSEGQIKLTATV 4TSD Chain:A ((2-180)) AIFGELSSLGHLFKKTQELEILHEYLKEVMQKGSKANQRVLNLATNTEFQVPLGHGIFSIEQSYCLEHAKESEKGFFESHKKYVDFQLIVKGVEGAKAVGINQAVIKNPYDEKRDLIVYEPVSEASFLRLHAGMLAIFFENDAHALRFYGESFEKYREEPIFKAVVKAPKGLIKLKLAA

General information: TITO was launched using: RESULT: Template: 4TSD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 706 26415 37.42 167.18 target 2D structure prediction score : 0.37 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : 37.42 2D Compatibility (Sec. Struct. Predict.) : 0.37 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.221

(partial model without unconserved sides chains): PDB file : Tito_4TSD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4TSD-query.scw PDB file : Tito_Scwrl_4TSD.pdb: