Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSILVIADHNNQTLNGATLNVVAAAQ--KIGGDITVLVAGSGAQAVADAAA-KVAGVSKVLLADNAAY---ANQLAENVAGLVADLAKGYKYVLAASTTTGKNILPRVAALLDVSMITDIISVESANTFKRPIYAG-NAIATVQSD---EAIIVGTVRGTAFDPVAAEGGSAAVETVGEVKDAGV-SKFVSEEIVKLDRPELTAARIVVSGGRGVGSGENYHKVLDPLADKLGAAQGASRAAVDAGFVPNDFQVGQTGKIV-APELYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPINSVADYWLVGDLNAVVPELVSKL 1O96 Chain:F ((3-318)) --ILVIAEHRRNDLRPVSLELIGAANGLKKSGEDKVVVAVIGSQADAFVPALSVNGVDELVVVKGSSIDFDPDVFEASVSALIA--AHNPSVVLLPHSVDSLGYASSLASKTGYGFATDVYIVEYQGDELVATRGGYNQKVNVEVDFPGKSTVVLTIRPSVFKPL--EGAGSPV--VSNVDAPSVQSRSQNKDYVEV-DIDITTVDFIMSIGRGIGEETNVEQFRE-LADEAGATLCCSRPIADAGWLPKSRQVGQSGKVVGSCKLYVAMGISGSIQHMAGMKHVPTIIAVNTDPGASIFTIAKYGIVADIFDIEEELKAQL

General information: TITO was launched using: RESULT: Template: 1O96.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain F - contact count / total energy / energy per contact / energy per residue : 1588 2699 1.70 9.00 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain F : 0.81 3D Compatibility (PKB) : 1.70 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.81 QMean score : 0.455

(partial model without unconserved sides chains): PDB file : Tito_1O96.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1O96-query.scw PDB file : Tito_Scwrl_1O96.pdb: