Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHCQDTLAKAEETLTKMMTESNEEVDFDGNEES 1Q2Z Chain:A ((19-57)) ----SFEEASNQLINHIEQFLDTNE-----TPYFMKSIDCIRAFREEA--------------------------

General information: TITO was launched using: RESULT: Template: 1Q2Z.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 49 -8146 -166.24 -208.87 target 2D structure prediction score : 0.85 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -166.24 2D Compatibility (Sec. Struct. Predict.) : 0.85 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.838

(partial model without unconserved sides chains): PDB file : Tito_1Q2Z.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1Q2Z-query.scw PDB file : Tito_Scwrl_1Q2Z.pdb: