Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGQLTDASVVLRFGYQAIRRAGLPTEEILTKAGVALNQVDTNARTPLSAQYAFWTAAQEVSKDPDIGLHLGEHL-PLYRGQVIEHLFNSSETFGEGLKRALAYQRLISDAFD-AKLVVE-DG-R--CYLTNGEQVGADNLVNRHF-SECAI-SGVLRFFKFITEG-QFHPIFIDFNFSEGASEDEYFRVYGCPVSLGQKETRLYFDPAILDFQLWQAEPELLQLHEQLAIEKLQELA--R-YDLVGEVRRAIGSTLESGETTLETVAAQLNITPRRLRTQLSEANTSFQQILSDYRCRLAKKLLANTNESVERIVYLTGFSEPSTFYRAFKRWTNETPVEYRKRKQHR 5CHH Chain:A ((12-328)) ---------------------WRPLNNYLAVQRITP---------PRLPSEALYEWIVLNGRSPLEGLSLGEHYRLSDYG-VAGLALQSAGTVGEALQLIKTNMLLFRKDIRGIAVRRSSCDTVDVDIDLQDKPD--WPQSARLYHANV-LASAAYAVFRDLL-LGELELVRLRLPERN-GDVRAYEEYFRVPVYFAGAGITFTLPEELLEAEIATANSAVFQASLALGSKAFNTRVTREMGGYRQRIVALLEV-LQDRYPSIAWVARQLKVTERTLRRRLADEGTNYREVLDLVRHDRARQLLRDERLRIEEVAERLGYMDTSSFRHAFRRWTGQCANDYRQA----

General information: TITO was launched using: RESULT: Template: 5CHH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1295 -18623 -14.38 -63.13 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -14.38 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.443

(partial model without unconserved sides chains): PDB file : Tito_5CHH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5CHH-query.scw PDB file : Tito_Scwrl_5CHH.pdb: