Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQEVYCVMIEKSINPHDYQHIHSPASVMPKNYHAKHRIDLHQHERGQLIYATSGIMELSTEE--ELWLIPPRFGVWIPAYTPHQMTTK----TDVHLNTLYIDTYRWSKP-FPD---K---------P-CGV--TVSGLLHELLIRAASFP--IEYPLHSVEWKTMDLLVEELKWTKGISLMTPEPYMDKRLQDLCNILIINPADNHSLEEWSSQVGATTRTLSRLFKQEMNTTFTLWRQQLRIVHAIPSLMAG-KPISDISQELGYSSQSTFTVMFKKIMGKTPTEYIAWANGNPTTFD 4MLO Chain:A ((8-272)) -----------------------QTNVYRMSKFDTYIFNNLYINDYKMFWIDSGIAKLIDKNCLVSYEINSSSIILLKKNSIQRFSLTSLSDENINVSVITISDSFI-RSLKSYILGDLMIRNLYSENKDLLLWNCEHNDIAVLSEVVN-FREINYSDEFLKVFFSGFFSK-VEKKYN--SIFITD-DLDAMEKISCLVKSDITRNWRWADICGELRTNRMILKKELE-SRGVKFRELINSIRISYSISLMKTGEFKIKQIAYQSGFASVSYFSTVFKSTMNVAPSEYLFMLTG------

General information: TITO was launched using: RESULT: Template: 4MLO.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1017 -13650 -13.42 -57.11 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -13.42 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.459

(partial model without unconserved sides chains): PDB file : Tito_4MLO.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4MLO-query.scw PDB file : Tito_Scwrl_4MLO.pdb: