Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQLSKLLDHWFPHPFVSFLIIIFWLMLAHSLDASDLLMAVILGLVIPRLVRPFITRTPHIHWKPAIKLCFVVLWDIIISNFRVAKLVLGPPKKLHPKWYRVPLETEHEQVNSLLAMIITTTPGTVSAGIDQERGDILVHSLSTENTESDVQDIKQRYEAPLIEIFDVKSKSEDNA- 1Q0V Chain:A ((249-329)) ----------------------------------------------------------------------------------------------MDRDYSTP-EDEEELIRKAIELSLKESRNSASSEPIVPVVESKNEVKRQEIEEEEDPDLKAAIQESLREAEEAKLRSERQKA

General information: TITO was launched using: RESULT: Template: 1Q0V.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 20 3824 191.18 47.79 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.48 3D Compatibility (PKB) : 191.18 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.48 QMean score : 0.298

(partial model without unconserved sides chains): PDB file : Tito_1Q0V.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1Q0V-query.scw PDB file : Tito_Scwrl_1Q0V.pdb: