Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRCNVMKILIIDNYDSFTFNLYQLLGEILISLKSRKEISDFEIVVKRNN---EISLDEIRKLEFDRIIISPGPGSPDDERYFGISKQVILQLGKEIPILGVCLGMQGIAYCFGGKVIRAKLPMHGKISTINHSDSGVFSGIPQDVEVMRYHSLIVDSSTLPECFIVTARVNSAYSDSEEEIMGIKHQTYPIEGVQFHPESFASEAGKTLLQNFVHSKL 1I7Q Chain:D ((4-191)) -------ILLLDNVDSFTYNLVDQL-----------RASGHQVVIYRNQIGAEVIIERLQHMEQPVLMLSPGPGTPSEA---GCMPELLQRLRGQLPIIGICLGHQAIVEAYGGQVGQAGEILHGKASAIAHDGEGMFAGMANPLPVARYHSLV--GSNIPADLTVNARFG-------EMVMAVRDDRRRVCGFQFHPESILTTHGARLLEQTLAWAL

General information: TITO was launched using: RESULT: Template: 1I7Q.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 1072 -42393 -39.55 -229.15 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain D : 0.78 3D Compatibility (PKB) : -39.55 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.494

(partial model without unconserved sides chains): PDB file : Tito_1I7Q.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1I7Q-query.scw PDB file : Tito_Scwrl_1I7Q.pdb: