Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MMNSSTEQIISNSLSLRLKQETAAEHERMHQLMSE---AKVFSSKEKYAQFTLSQYYFQLEIEHLFEKEGVAGL--IPDLDIRGRSKQALADLNDLGIQPNGQ-----Q---------LQSENVQLPEALGWIYVSE-GSTLGAAFLFKEAQKHLGFSETFAARNLAAYPEGRA-KVWKRFVKALDEAGFDQTQQDRVVQGALDAFGYFGQALDQLDELK 1WE1 Chain:A ((2-208)) ----------SVNLASQLREGTKKSHSMAENVGFVKCFLKGVVEKNSYRKLVGNLYFVYSAMEEEMAKFKDHPILSHIYFPELNRKQSLEQDLQFYYGSNWRQEVKISAAGQAYVDRVRQVAATAPELLVAHSYTRYLGDLSGGQILKKIAQNAMNLH-DGGTAFYEFADIDDEKAFKNTYRQAMNDLPIDQATAERIVDEANDAFAMNMKMFNELEG--

General information: TITO was launched using: RESULT: Template: 1WE1.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 676 24972 36.94 134.26 target 2D structure prediction score : 0.72 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : 36.94 2D Compatibility (Sec. Struct. Predict.) : 0.72 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.406

(partial model without unconserved sides chains): PDB file : Tito_1WE1.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1WE1-query.scw PDB file : Tito_Scwrl_1WE1.pdb: