Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDFDFNLILVPVTLILFAVWLLDKLVFKQRANKGRENENFVITWAYDFWPVLAVVLVLRSFTYEPFNIPSDSMVPTLETGDFILVNKFDYGVRLPIVNKKVIDVGEPKRGDVIVFRYPPQPTISYIKRVIGLPGDHIVYD--HGQLII-----NGQKIP-KVPTQFS--REKDALDTPTSIYHKETIGDHTFTMREL-------EGVNVARQAPFINYVDN------------GKYANQDGLYWEV-TVPKGHYFAMGDNRDQSADSRFWGFVPEENLTGRAFYVWMHKEPGFHLPSFNRNGKID 1T7D Chain:B ((7-228)) -------------------------------------------------------------IYEPFQIPSGSMMPTLLIGDFILVEKFA-------------ETGHPKRGDIVVFKYPEDPKLDYIKRAVGLPGDKVTYDPVSKELTIQPGCSSGQACENALPVTYSNVEPSDFVQT----FS--------SGFFEVPKNETKENGIRLSERKETLGDVTHRILTVPIAQDQVGMYYQQPGQQLATWIVPPGQYFMMGDNRDNSADSRYWGFVPEANLVGRATAIWM------------------

General information: TITO was launched using: RESULT: Template: 1T7D.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 694 -14056 -20.25 -82.20 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain B : 0.68 3D Compatibility (PKB) : -20.25 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.435

(partial model without unconserved sides chains): PDB file : Tito_1T7D.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1T7D-query.scw PDB file : Tito_Scwrl_1T7D.pdb: