Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAAGGAAAA-----EEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAP---VKEGVSKEEAEELKAKLEEVGASVTVK 1DD4 Chain:B ((1-107)) --MTIDEIIEAIEKLTVSELAELVKKLEDKFGVTAAAPVAVAAAPVAGAAAGAAQEEKTEFDVVLKSFGQNKIQVIKVVREITGLGLKEAKDLVEKAGSPDAVIKSGVS---------------------

General information: TITO was launched using: RESULT: Template: 1DD4.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 231 -3740 -16.19 -37.77 target 2D structure prediction score : 0.77 Monomeric hydrophicity matching model chain B : 0.83 3D Compatibility (PKB) : -16.19 2D Compatibility (Sec. Struct. Predict.) : 0.77 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.624

(partial model without unconserved sides chains): PDB file : Tito_1DD4.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1DD4-query.scw PDB file : Tito_Scwrl_1DD4.pdb: