Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence CFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNPKTFVLSMSHGQKIKHFQIIPVEDDGEMFHTLDDGHTRFTDLIQLVEFY 3PQZ Chain:D ((17-97)) -FHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLILPSEE--RLYFSMDDGQTRFTDLLQLVEFH

General information: TITO was launched using: RESULT: Template: 3PQZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 286 -47214 -165.08 -597.65 target 2D structure prediction score : 0.81 Monomeric hydrophicity matching model chain D : 0.92 3D Compatibility (PKB) : -165.08 2D Compatibility (Sec. Struct. Predict.) : 0.81 1D Compatibility (Hydrophobicity) : 0.92 QMean score : 0.649

(partial model without unconserved sides chains): PDB file : Tito_3PQZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3PQZ-query.scw PDB file : Tito_Scwrl_3PQZ.pdb: