Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVADQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERKGISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKVGTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY 1KAQ Chain:F ((7-189)) -----------------------KKIGIFGGTFDPPHNGHLLMANEVLYQAGLDEIWFMPNQI----------DSFHRVEMLKLAIQSNPSFKLELVEMEREGPSYTFDTVSLLKQRYPNDQLFFIIGADMIEYLPKWYKLDELLNLIQFIGV------VETPYPLLFADVPEFEVSSTMIRERFKSKKPTDYLIPDKVKKYVEEN---

General information: TITO was launched using: RESULT: Template: 1KAQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain F - contact count / total energy / energy per contact / energy per residue : 785 -137519 -175.18 -823.46 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain F : 0.82 3D Compatibility (PKB) : -175.18 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.82 QMean score : 0.573

(partial model without unconserved sides chains): PDB file : Tito_1KAQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1KAQ-query.scw PDB file : Tito_Scwrl_1KAQ.pdb: