Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLKKYFSKYKWTDLFWILFVILTCLYIGNHDLFT-LNHQEFSFRGSVWGLVLALYHLLFIDKFVIS------NRK-- 2JVE Chain:A ((18-88)) MALKCFTRNGDDR------TVTTCAEEQTRCLFVQLPYSEIQECKTVQQCAEVLEEVTAIGYPAKCCCEDLCNRSEQ

General information: TITO was launched using: RESULT: Template: 2JVE.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 229 -18717 -81.73 -301.88 target 2D structure prediction score : 0.47 Monomeric hydrophicity matching model chain A : 0.56 3D Compatibility (PKB) : -81.73 2D Compatibility (Sec. Struct. Predict.) : 0.47 1D Compatibility (Hydrophobicity) : 0.56 QMean score : 0.199

(partial model without unconserved sides chains): PDB file : Tito_2JVE.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2JVE-query.scw PDB file : Tito_Scwrl_2JVE.pdb: