Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNTFVDAARSFRTQFDLNFSEKIIVDFFAGGGGASTGLEMGLNR-PVYVAVNHNPKAISMHEANHPHAKHYIQDVFAVDPI------------DICDGHQVGWFHASPDCTHHSQAAGGQPR--KKEIRDLSWVVLKFAGKVKPDVISLENVKQILGWGPLIAKRDKATGRVITLDKININGKKVNRIAEPGERVPRHNQFLVPNPKKKGKTWKHFVRSLEQLGYEVEWQKNIIAADFGAPTKRERLFLIARCDGQPI-VWPEKYFSKKPK---------------------GNLKKWRSTVECVDFSDLGNSIFDRPQGPLADATLKRIAKGIQKYVIETKEPFFVNSSTPFIGRDFRTSFGHDIREPLATTTAGYGGH------SSLISPILVPFITEFANASQQRNWSIDEPLSTICAQVKGGHHGLVT----------------------------------------------------AKLSKDNYKGALRVAAFLINYYGNGDARSITEPMDTITTKDRLVLVTVWIKGEPWAIVDICIRMLKPRELFRAQGVPDSYVIEYGSDGKPLSKKDQVFMVGNSVSPYPMAAIARANNPFITQQIKGAA 3SWR Chain:A ((537-1001)) -----------------KLPKLRTLDVFSGCGGLSEGFHQA-GISDTLWAIEMWDPAAQAFRLNNPGSTVFTEDCNILLKLVMAGETTNSRGQRLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFKNSLVVSFLSYCDYYRPRFFLLENVRNFVSFKR-------------------------------------------------SMVLKLTLRCLVRMGYQCTFGV-LQAGQYGVAQTRRRAIILAAAPGEKLPLFPEPLHVFAPRACQLSVVVDDKKFVSNITRLSSGPFRTITVRDTMSDLPE-VRNGAS-ALEIS-----------------------------------------YNGEPQSWFQRQLRGAQYQPILRDHICKDMSAL---------VAARMRHIPLAPG------SDWRDLPNIEVRLSDGTMARKLRYTHHDRKNGRSSSGALRGVCSCVEAGKACDPAARQFNTLIPWCLPHTGNRHNHWAGLYG---RLEWDGFFSTTVTNPE-----PMGK-QGRVLHPEQHRVVSVRECARSQGFPDTYRLF------GN-ILDKHRQVGNAVPPPLAKAIGLEIKLCMLAK-----

General information: TITO was launched using: RESULT: Template: 3SWR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1592 17294 10.86 46.74 target 2D structure prediction score : 0.50 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : 10.86 2D Compatibility (Sec. Struct. Predict.) : 0.50 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.323

(partial model without unconserved sides chains): PDB file : Tito_3SWR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3SWR-query.scw PDB file : Tito_Scwrl_3SWR.pdb: