Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ---MTTLTCFKAYDIRGKLGTELNEEIAYKIGRAYGQIYKPK---TVVVGCDIRLSSEALKQAAIRGLNDAGVNVLDLGMTGTEEVYFAAFHLDVQGGIEVTASHNPMDYNGMKLVRENARPISADTGLKEIQALAETNNFEEVGQKGTTQSYNILPEFVDHLLTYIEPAKIRPLKLVVNAGNGAAGHVIDAIEEKFKALNVPVEFIKIHHEADGTFPNGIPNPILIENRDSTRNAVLEHKADMGIAWDGDFDRCFLFDEKGQFIEGYYIVGLLAQAFLIKQSGEKIVHDPRLVWNTFDIVDEYKGVTVQSKSGHAFIKDVMREHNAVYGGEMSAHHYFRDFAY-CDSGMIPWLLTIVLLSETGQSLSTLVENMIAKFPCSGEINFKVADT--QTTIQKIFDFYADQNPQIDRTDGVSLNFGAWRFNVRASNTEPLLRLNIESRADRQAQPMQYYVDELTGLIQN------ 1K2Y Chain:X ((5-463)) KAPTLPASIFRAYDIRGVVGDTLTAETAYWIGRAIGSESLARGEPCVAVGRDGRLSGPELVKQLIQGLVDCGCQVSDVGMVPTPVLYYAANVLEGKSGVMLTGAHNPPDYNGFKIVVAGETL--ANEQIQALRERIEKNDLAS--GVGSVEQVDILPRYFKQIRDDIAMAK--PMKVVVDCGNGVAGVIAPQLIEAL-----GCSVIPLYCEVDGNFPNHHPDPGKPENLKDLIAKVKAENADLGLAFDGDGDRVGVVTNTGTIIYPDRLLMLFAKDVVSRNPGADIIFDVKCTRRLIALISGYGGRPVMWKTGHSLIKKKMKETGALLAGEMSGHVFFKERWFGFDDGIYSAARLLEILSQDQRDSEHVFSAF-PSDISTPEINITVTEDSKFAIIEALQRDAQWGEGNITTLDGVRVDYPKGWGLVRASNTTPVLVLRFEADTEEELERIKTVFRNQLKAVDSSLPVPF

General information: TITO was launched using: RESULT: Template: 1K2Y.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain X - contact count / total energy / energy per contact / energy per residue : 2756 69523 25.23 156.58 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain X : 0.75 3D Compatibility (PKB) : 25.23 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.504

(partial model without unconserved sides chains): PDB file : Tito_1K2Y.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1K2Y-query.scw PDB file : Tito_Scwrl_1K2Y.pdb: