Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIQTETMLDVADNSGARRVQCIKVLGGSHRRYASVGDIIKVTVKEAIPRARVKKGDVMNAVVVRTKFGIRRPDGSVIRFDDNAAVILNNNKAPIATRIFGPVTRELRIEQFMKIISLAPEVL 1WHI Chain:A ((1-122)) MIQQESRLKVADNSGAREVLVIKVLGGSGRRYANIGDVVVATVKDATPGGVVKKGQVVKAVVVRTKRGVRRPDGSYIRFDENACVIIRDDKSPRGTRIFGPVARELRDKDFMKIISLAPEVI

General information: TITO was launched using: RESULT: Template: 1WHI.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 645 -84397 -130.85 -691.78 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.91 3D Compatibility (PKB) : -130.85 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.91 QMean score : 0.578

(partial model without unconserved sides chains): PDB file : Tito_1WHI.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1WHI-query.scw PDB file : Tito_Scwrl_1WHI.pdb: