Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MYKMTRRSTMLETYLEKSIFRQVYICEQLHEK-GTIQIREIADQLNVCPLTVTNDLECITDILHQQIISVEKSRSSFTVAFDSSFSRLALTQLIYQRSDFFNVLGHYLSGEH-NWSNIADTTFISLSKVYNLRNELINFFKQMQYLNAD--GHFEIPEKDYRSLLLTIIYETNRTELIQLNKSIIQSGQQLIDYVEKHFFSRSYPTVEKQFILLGIAIGLQRSKTNPIYFSQEE-KRVARHTPLFQLIQK---GLEQLSFSLCHDEDECLYIYFLFNSR-NYLCDNFELLQKDLNVVYQNHVADNPLVIELSQKLILSLNISEENQILFDKALLPFIRSLWADIQIFQP----DKTYLLNEEQRALYLEVHEILEQWRKQNNLFLRWNENSIRKLTISLSLLNEHKRKSPIEVFIVAPSDFRY-LYYRQQLEDILGEHFSISNIICKQLREIVDDTFFCTQRIILCDSSLYQEGLGSEKTIIYPITFQTIHTVIDQLNKQI 4R6I Chain:B ((3-476)) -------AMLTPISIEKEHIRLINLLHFINEQNRWFTIKELSDYLQVADKTVRKYLKLLEDEIPPSWNLLVQKGKGIYLKKPLNESLSFVESKILRKSLNLQICEELVFK-KNSMQSLAQKLHLQVGALYPIINQINYDIQSSHLNIKKKPLEISGREQDVRVFMLRLYCNIPNDYWPFPYINK-QNITDLINKMEKIL-NVQMYTYSKHKLCVLFAITISRLLSGNTIDNVSGLILVNKNDDHYKTVASITSELQNS-FGVTLHETEISFLALALLLSLGNSIT---NKT--L---TSYKKTIMPLAKEITKGIEHKLQLGINYDESFLTYVVLIIKKALDKNFIQYYNYNIKFIRHIKQRHPNTFNTIQECISNLNYTVYS--HFDCYEISLLTMHFETQRMLFKNNPKKIYVYTSQGCIHREYISALLEKRYNGLIKIVRNTI-----------DMEIDIIISN-------------------EFPTERDFHEIKK--

General information: TITO was launched using: RESULT: Template: 4R6I.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1856 16259 8.76 37.46 target 2D structure prediction score : 0.51 Monomeric hydrophicity matching model chain B : 0.63 3D Compatibility (PKB) : 8.76 2D Compatibility (Sec. Struct. Predict.) : 0.51 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.357

(partial model without unconserved sides chains): PDB file : Tito_4R6I.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4R6I-query.scw PDB file : Tito_Scwrl_4R6I.pdb: