Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MHDPVLESHHLVCEKPQTRRGIERRLALLLSATELFLEKGYDAVSLDDIVNHAGGSKTSIYKYFGNKDGLFTAICDYRREMFFKDICIAFQPEQTSLKDYLIQTLIRFYKHIIQPEHIAFLRLVIEQT-QCNATLSQYLYEKCALDVQNTIAQALLISHQSGEITCTFPDHSSLMYFGILRD-IEWRTIMGMPLPPNETEVIDYINYCVDIFLKGHHKV 3C2B Chain:B ((13-206)) --------------------FSPRQNAVLDQALRLLVEGGEKALTTSGLARAANCSKESLYKWFGDRDGLLAAMITFQQSKV-------DRVSAPQLADHLEVFAHDLLDVLAGDVSLALNRLAIGQASRDGSKLGDLLLERGRRQIDRRARGLIEAGRRSGYLRFDDAEEAYRSFYGLIVSDLHVRMLLGEA---PD-DFSARAKKAVVAFLTLYG--

General information: TITO was launched using: RESULT: Template: 3C2B.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 694 -73464 -105.86 -399.26 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain B : 0.70 3D Compatibility (PKB) : -105.86 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.540

(partial model without unconserved sides chains): PDB file : Tito_3C2B.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3C2B-query.scw PDB file : Tito_Scwrl_3C2B.pdb: