Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence WYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQH 2LNW Chain:A ((24-98)) WFAGNMERQQTDNLLKSHASGTYLIRERPAEAERFAISIKF---------------NDEVKHIKVVEKDNWIHIT---EAKKFDSLLELVEYY

General information: TITO was launched using: RESULT: Template: 2LNW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 265 -37794 -142.62 -503.92 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -142.62 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.479

(partial model without unconserved sides chains): PDB file : Tito_2LNW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2LNW-query.scw PDB file : Tito_Scwrl_2LNW.pdb: