Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MINQKEGDFLRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTPAENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQELKAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTFRTKIRKWKKIVL 5CQV Chain:B ((13-183)) ----------RTYSDKNELKEEVLKSYKKYIAEFNDIPEKLKDLRIDEVDRTPAENLAYQVGWTTLILKWESDEQSGLEVKTPTETFKWNQLGELYQHFTETYASLTIKELTAQLNDNVDAIGNMIDSMSDEVLFKPHMRNWADSATK--VWEVYKFIHINTVAPFGTFRTKIRKWKKVAL

General information: TITO was launched using: RESULT: Template: 5CQV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 461 -8410 -18.24 -49.76 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain B : 0.91 3D Compatibility (PKB) : -18.24 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.91 QMean score : 0.458

(partial model without unconserved sides chains): PDB file : Tito_5CQV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5CQV-query.scw PDB file : Tito_Scwrl_5CQV.pdb: